
Emily Tomlinson, MD
I am a clinical pediatric hematology/oncology fellow at UCSF. My research interests include improving outcomes in pediatric leukemia through mitigation of treatment toxicity and further understanding its pathogenesis, especially in underserved populations. My project in the Avagyan lab explores the role of environmental risk factors associated with adverse social determinants of health in the prenatal origin of leukemia-predisposing clones in utero through inflammatory pathway upregulation. Unlike many poor prognostic predictors of pediatric B-cell acute lymphoblastic leukemia, environmental risk factors are modifiable. Understanding inflammatory pathways involved with environmental stressors would allow for targeting protective biologic mechanisms, to one day alter the course of pre-leukemia by early identification and prevention of progression.