Bibhudev Barik, PhD

Postdoc, 2026
Postdoctoral fellow
Pediatric Blood and Marrow Transplantation

I am a Postdoctoral Scholar in the Avagyan Lab at UCSF. I earned my Ph.D. from the Institute of Life Sciences in India, where I identified novel regulatory roles for the RNA-binding protein PTBP2 in leukemia cell survival, disease progression, and metabolism through its regulation of autophagy. I am passionate about translational research, and my goal is to bridge benchside discoveries to clinical applications to improve patient outcomes in hematologic conditions.

In the Avagyan Lab, my research focuses on the molecular mechanisms of clonal hematopoiesis and bone marrow failure syndromes. Specifically, I am investigating the pathogenesis of MDS driven by germline GATA2 deficiency and how these genetic alterations facilitate the acquisition of somatic mutations, clonal evolution, and the onset of MDS. Using a GATA2-deficient zebrafish model, I am investigating clinically relevant questions about the pathogenic mechanisms of clonal hematopoiesis and MDS driven by acquired somatic mutations. Overall, my main objective of life is to serve mankind.